158 Max HP in Slay the Spire
This was one of my favorite decks in slay the spire. I started early with a card that gains me +3 MAX HP if it kills an enemy. I ended the game with 158 health!
The deck was most fun because I had dead wood (iirc), which gives you a random card whenever a card is exhausted. That synergized with energy gain and a 'draw when card exhausts' trigger, among others.
